KOSÉ

KOSÉ’s No.1 Brightening Serum Powered by Effective Anti-Dark Spots Approaches at the Source for Instant Clarity     A RESEARCH COLLABORATION between KOSÉ and THE KURUME UNIVERSITY SCHOOL OF MEDICINE A first in Japan, KOSÉ performed 3D analysis on dark spots formation to learn how to stop unwanted melanin at the source by studying the transfer of melanosomes from melanocytes to epidermal cells. We set out to better understand the structure of pigmented areas in the skin so that we can come up with a more effective approach to brightening. The result is our instant skincare range, One by KOSÉ, that decolorises dark spots at their source with four powerful and unique ingredients acting directly on areas deep in the skin that produce pigmentation. Concentrations of melanin are prevented from darkening. Clear, glowing skin is achieved from the moment of application.   NEW RESEARCH FINDINGS #1 When the skin is impacted by UV rays, hormonal imbalance, stress and environmental factors, epidermal cells send a signal to produce melanin pigments as a form of protection. Melanocytes in the skin start producing the tyrosinase enzyme, attacking the originally colourless tyrosine to darken and become melanin pigments. These pigments are contained in a sack called melanosomes that will push out, break and disperse when they reach epidermal cells. There are four types of melanosomes: Type I to III have not been transferred to epidermal cells, therefore have yet to become dark spots. But Type IV melanosomes have reached epidermal cells and break to disperse. If this process doesn’t take place smoothly, pigment clots will remain, causing dark spots in the skin. To prevent this, we must stop melanosomes from reaching Type IV.   #2 Melanocytes in pigmented areas stretch out from the bottom to the top of epidermal cells, binding the cells. Dendrites (or neurons) from these melanocytes then transfer large amounts of dark Type IV melanosomes to the cells. This is how melanosomes are transferred to the skin, causing dark spots to appear.   OUR NEW APPROACH Towards faster and more reliable brightening effects Our research collaboration has resulted in two solutions to eliminate dark spots at the source for brightening on new levels.   A SPECIAL FORMULATION 4 Powerful Ingredients in 1 Bottle   CHINESE QUINCE EXTRACT To suppress melanocyte activation by subduing the signal to create melanin, preventing epidermal cells from receiving large amounts of melanin   RESVERATROL An antioxidant effective at minimising the production of melanin by reducing tyrosinase levels in skin thus decolorising dark spots and reducing melanin levels   KOJIC ACID A reliable brightening agent for 32 years and counting. Works on melanocytes directly by capturing the copper ions that activate tyrosinase and effectively suppresses excessive melanin production. Compared to other brightening agents, kojic acid has the lowest molecular weight, allowing it to penetrate almost instantly into skin for fast anti-dark spots action almost similar or more effective than the popular whitening agent hydroquinone used by doctors for the same effect after a laser treatment^* * Shinyaku & Rinsho, January 2013   MESHIMAKOBU EXTRACT A fungus shown to be effective on dark spots and has been used since the olden days in Japan. Reduces tyrosinase and inhibits the maturation of melanosomes, preventing the overproduction of Type IV melanosomes   INCREDIBLE BRIGHTENING EFFECTS Instant, immediate skincare. Decolorises dark spots at their source. Now even more effective by acting directly deep in the skin of pigmented areas for flawless, glowing skin.   NO MORE DARK SPOTS ADVANCED BRIGHTENING SERUM FOR CLEAR FLAWLESS SKIN     ONE BY KOSÉ Melanoshot White D 40ml, RM208     PRODUCT FEATURES Decolorises dark spots at their source Four powerful and unique ingredients take direct action at the source to cut melanin production at the root, preventing unwanted skin pigmentation.   High skin affinity Its highly permeable base dissolves into even dry, sun-damaged skin in an instant, allowing the formula to spread easily throughout the skin.   Instant, immediate skincare Skin appears soft and glowing immediately after application. See instant results of smooth and clear skin after each use.     HOW TO USE Every morning and evening after using your toner, press the pump to release a small amount onto your hand. Spread gently across your face.     INGREDIENTS Kojic acid, phellinus linteus extract, Chinese quince extract, concentrated glycerine, glycosyl trehalose, concentrated glycerin, resveratrol